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phenobarbital will lower the extent or influence of olanzapine/samidorphan by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Keep away from or Use Alternate Drug. Sturdy CYP3A4 inducers lessen levels of olanzapine and samidorphan by~fifty% and ~75% respectively.Tend not to give to pets with critical respiratory dysfunction, liver sickness,